Authors
1 Assistant Professor, Faculty of Pharmacy, Zanjan University of Medical Sciences
2 PhD Student in General Pharmacy - Zanjan University of Medical Sciences
3 Zanjan University of Medical Sciences
4 Research Institue of Modern Biological Techniques, University of Zanjan, Zanjan, Iran
Abstract
Bacterial resistance is one of the problems in the world of medicine today. Many efforts are underway to find alternative methods, one of which is to use the capacity of native plants of each region. The chamber was powdered as a homogeneous mixture and its essential oil was extracted by water distillation. Then, the components of the essential oil were identified and the amount of the components was identified using a gas chromatography device connected to a mass spectrometer. GC-Mass analysis showed that the most important effective compounds with antimicrobial activity of this plant were 2- boronanone (12.36%), camphor (6.87%), 3-carn (5.35%). The range of growth inhibition zone varied from 9 to 40 mm. Essential oil with growth inhibition zone of 40 mm had the greatest effect against Staphylococcus aureus even in comparison with clindamycin, although essential oils had no effect on Pseudomonas aeruginosa and could not inhibit its growth. In general, essential oils had a better effect on gram-positive bacteria than gram-negative bacteria.
Keywords
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