Journal of Medicinal Plants Biotechnology

Bioformulation of silver nanoparticles using Nigella arvensis leaf extract with Potential Bioactivity against Klebsiella pneumonia

Author

Azam Chahardoli

Department of Biology, Faculty of Science, Razi University, Kermanshah, Iran

https://doi.org/10.30470/jmpb.2022.702225
Abstract
The formulation of nanoparticles mediated medicinal plant extract is cost-effective, eco-friendly, stable and quicker than conventional methods. These nanoparticles particularly bioformulated silver nanoparticles (AgNPs) using plant extracts are the most effective against bacteria. Therefore, in the present study, we determined the antibacterial activity of Nigella arvensis-derived AgNPs (Na-AgNPs) against an antibiotic resistance Klebsiella pneumonia using agar well diffusion and minimum inhibitory concentration (MIC). According to results, the bioformulated Na-AgNPs showed a maximum inhibition zone of 14 mm and MIC value of 15.62 μg/mL against K. pneumonia. Therefore, bioformulated Na-AgNPs as an alternative to chemical antibacterial agents can be used to manage of infections in medicine and other industries.

Keywords

Antibacterial activity
Antibiotic resistance
bioformulation
Klebsiella pneumonia
Journal of Medicinal Plants Biotechnology
Volume 7, Issue 2
February 2022
Pages 164-168

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